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For Librarians. RSS Feeds. Chemistry World. Education in Chemistry. Open Access. Historical Collection. You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page. Volume , Previous Article Next Article. Orlin D. Petsev b. You have access to this article. Please wait while we load your content Something went wrong. Try again? Cited by.
Back to tab navigation Download options Please wait Publication details The article was first published on 08 Apr Article type: Review Article. DOI: Download Citation: Annu. C: Phys. Velev, S. Gangwal and D. Petsev, Annu. Search articles by author Orlin D.
Sumit Gangwal. Dimiter N.
Nathan S. Copyright notice. The publisher's final edited version of this article is available at Nanoscale.
See other articles in PMC that cite the published article. Abstract Proteomic biomarkers of interest to the early diagnosis of diseases and infections are present at trace levels versus interfering species. Graphical abstract. Open in a separate window. Introduction Biomolecular assays require the quantitative identification of trace levels of biomarkers within bio-fluids that also contain common interfering species, such as circulating antibodies, at million to billion-fold higher levels.
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Figure 2. Influence of device geometry on force field For electrokinetic enrichment of biomolecules, we use the device structure of Fig. Effect of surface conduction on polarization time constant We validate the influence of colloidal size and surface charge on surface conduction in the double-layer by studying the polarization time constant of silica nanocolloids in 0. Frequency-selective enrichment molecular biomarkers Next, we investigate the application of polarization dispersion characteristics towards enabling selective enrichment of biomarkers in PBS media, namely PSA Fig.
Figure 7. Figure 8. Conclusions AC electrokinetics with a DC offset field is used to enable frequency-selective enrichment of molecular biomarkers within physiological media, using nanoslit devices. References 1.
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