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These ATG genes in yeast were the stepping stones to the explosion of research into the molecular analysis of autophagy in higher eukaryotes.
In the future, this research will help to design clinical approaches that can turn on autophagy and halt tumor growth. Toon meer Toon minder.
Experimental evidence pointed at autophagy as a pancreatic cancer cell mechanism to survive under adverse environmental conditions or as a defective programmed cell death mechanism that favors pancreatic cancer cell resistance to treatment. On the other hand, clearance of insoluble aggregate-prone proteins require formation of aggresomes. These can lead to mitochondrial swelling and depolarization. This entire panorama gives us a complex but exciting scenario. Schuck, S. S2 Data. The demographics of the ubiquitin system.
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Hayat, M. Honggang Wang Autophagy and Cancer , Springer-Verlag New York Inc. Autophagy and Cancer , Bekijk de hele lijst. We moved your item s to Saved for Later. There was a problem with saving your item s for later.
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Autophagy in mammalian systems, Part B. Preface. Klionsky DJ. Animals; Autophagy/physiology*; Biological Assay; Humans; Mammals/metabolism*. Chapter 1 Monitoring Autophagy in Mammalian Cultured Cells through the Dynamics of LC3. Shunsuke Kimura, Naonobu Fujita, Takeshi Noda, Tamotsu.
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