Part 2. Thermal and photo-induced rearrangements of propargylamine and allylamine radical cations in low-temperature freon matrices. PubMed: Reassessment of the structural composition of the alkenone distributions in natural environments using an improved method for double bond location based on GC-MS analysis of cyclopropylimines. PubMed: Electron paramagnetic resonance study of the mononuclear Al species formed in the reaction of Al atoms and cyclopropylamine at 77 k in an adamantane matrix.
PubMed: Cytochrome Pcatalyzed oxidation of N-benzyl-N-cyclopropylamine generates both cyclopropanone hydrate and 3-hydroxypropionaldehyde via hydrogen abstraction, not single electron transfer. PubMed: Pressure-induced polymorphism in cyclopropylamine. PubMed: Mutation of surface cysteine to alanine in monoamine oxidase A alters substrate turnover and inactivation by cyclopropylamines.
PubMed: Cyclopropylamine inactivation of cytochromes P role of metabolic intermediate complexes. Part 4: effects of aryl substituents and stereochemistry on the inhibition of monoamine oxidases by 1-arylfluoro-cyclopropylamines. PubMed: Inhibition of nucleoside transport proteins by C8-alkylamine-substituted purines. PubMed: Synthesis and properties of gem- difluorocyclopropyl amine derivatives of bicyclo[n. PubMed: Fluorinated phenylcyclopropylamines as inhibitors of monoamine oxidases. PubMed: Stereochemistry of cyclopropane formation involving group IV organometallic complexes.
PubMed: Preliminary evidence of the role of hydrogen peroxide in the degradation of benzo[a]pyrene by a non-white rot fungus Fusarium solani. PubMed: Molecular orbital calculations of ring opening of the isoelectronic cyclopropylcarbinyl radical, cyclopropoxy radical, and cyclopropylaminium radical cation series of radical clocks. PubMed: Early upregulation of kinin B1 receptors in retinal microvessels of the streptozotocin-diabetic rat. PubMed: Theoretical study of the mechanism of the formation of 3-unsubstituted 4,4-disubstituted beta-lactams by silver-induced ring expansion of alkoxycyclopropylamines: a new synthetic route to 4-alkoxycarbonylalkylazetidinones.
PubMed: Stereocontrolled synthesis of 3- transaminocyclopropyl alanine, a key component of belactosin A.
PubMed: Cyclopropane structural units from homoaldol adducts. PubMed: Formation of cyclopropanone during cytochrome Pcatalyzed N-dealkylation of a cyclopropylamine. PubMed: Synthesis and pharmacological evaluation of some pyridyl cyclopropylmethyl amines and their methiodides as nicotinic receptor ligands. PubMed: Inter-subunit cross-linking of methylamine dehydrogenase by cyclopropylamine requires residue alphaPhe PubMed: Radical cation-mediated annulation.
Stereoselective construction of bicyclo[5. PubMed: Detection of aminium ion intermediates: N-cyclopropyl versus N-carboxymethyl groups as reporters. PubMed: Effect of mobile phase amine additives on enantioselectivity for phenylalanine analogs. PubMed: N-dealkylation of an N-cyclopropylamine by horseradish peroxidase. Fate of the cyclopropyl group. PubMed: Enzymatic N-dealkylation of an N-cyclopropylamine: an unusual fate for the cyclopropyl group. PubMed: Characterization of the binding site of the histamine H3 receptor. Various approaches to the synthesis of 2- 1H-imidazolyl cyclopropylamine and histaminergic activity of 1R,2R - and 1S,2S 1H-imidazolyl -cyclopropylamine.
PubMed: Synthesis and serotonin receptor affinities of a series of trans indolyl cyclopropylamine derivatives. PubMed: A major role for prostacyclin in nitric oxide-induced ocular vasorelaxation in the piglet.
Ashley, M. Spiroannulated Cyclopropanes K. The in situ generated electrophilic carbene reacts smoothly with a broad range of alkenes and alkynes to provide the corresponding difluorocyclopropanes and difluorocyclopropenes within 10 min residence time at high reaction concentrations. Krishnamurthy, C. A reasonable level of enantioselectivity was obtained for the cyclopropanation of unfunctionalized olefins with chiral iodomethyl zinc species. The most recent reference I have found is from ref. Cited by.
PubMed: Novel cyclopropylamino -androsten-3,dione: a mechanism-based inhibitor of aromatase. PubMed: Mechanisms of the biphasic effects of peroxides on the retinal vasculature of newborn and adult pigs. PubMed: Mechanistic studies on the monoamine oxidase B catalyzed oxidation of 1,4-disubstituted tetrahydropyridines.
PubMed: In vitro anti-Mycobacterium avium activities of quinolones: predicted active structures and mechanistic considerations.
PubMed: Synthesis, structure, and antitumor activity of 1,3-dithiol- and 1,3-dithiolanylidenemalonatoplatinum II complexes. PubMed: Reaction of lysyl oxidase with transphenylcyclopropylamine. PubMed: Inhibition and activation of porcine squalene epoxidase. PubMed: Inhibition of cholesterol synthesis by cyclopropylamine derivatives of squalene in human hepatoblastoma cells in culture. PubMed: Synthesis of [carbonylC]sparfloxacin.
PubMed: Inhibition by cyclopropylamine of the quinoprotein methylamine dehydrogenase is mechanism-based and causes covalent cross-linking of alpha and beta subunits. PubMed: Oxidation of cycloalkylamines by cytochrome P Mechanism-based inactivation, adduct formation, ring expansion, and nitrone formation.
PubMed: Deprenyl antagonizes acute lethality of 1-methylphenyl-1,2,3,6-tetrahydropyridine in mice.
PubMed: Microscale syntheses of anti-tumour platinum compounds labelled with Pt. PubMed: In vivo distribution studies of radioactively labelled platinum complexes; cis-dichlorodiammine platinum II , cis-trans-dichlorodihydroxy-bis- isopropylamine platinum IV , cis-dichloro-bis-cyclopropylamine platinum II , and cis-diammine 1,1-cyclobutanedicarboxylate platinum II in patients with malignant disease, using a gamma camera. The versatility of this reaction is illustrated by the formation of key intermediates for the formal syntheses of cascarillic acid and grenadamide.
Rudolph, B.
Maci, A. Minnaard, B. Feringa, J. Methyl 1-arylamino-cyclopropane carboxylates have been readily synthesized in high yields by Rh-catalyzed decomposition of aryldiazoacetates in the presence of N-vinylphthalimide. The reaction is highly trans -selective.
Melby, R. Hughes, T. Hansen, Synlett , , Chandrasekhar, Ch. Narasihmulu, V. Jagadeshwar, K. Venkatram Reddy, Tetrahedron Lett. Dirhodium tetrakis- R - 1- 4-bromophenyl -2,2-diphenylcyclopropanecarboxylate Rh 2 R-BTPCP 4 is an effective chiral catalyst for enantioselective reactions of aryl- and styryldiazoacetates. Qin, V. Boyarskikh, J. Hansen, K. Hardcastle, D. Musaev, H. Davies, J. Hartikka, P. Arvidsson, J. Phenyliodonium ylides provide easy access to various 1,1-cyclopropane diesters using rhodium or copper catalysis and are safer and convenient alternatives to the corresponding diazo compounds.
Goudreau, D. Marcoux, A. Three highly enantio- and diastereoselective one-pot procedures for the synthesis of cyclopropyl and iodocyclopropyl alcohols with up to four contiguous stereocenters are reported. Route 1 and 2 involve asymmetric addition of an alkylzinc reagent to an enal followed by diastereoselective cyclopropanation using either diiodomethane or iodoform to generate the zinc carbenoid, leading to cyclopropyl or iodocyclopropyl alcohols, respectively.
Route 3 entails asymmetric vinylation of an aldehyde with divinylzinc reagents and subsequent diastereoselective cyclopropanation. Kim, A.
Lurain, P. Garcia-Carcia, P. Carroll, P. Walsh, J. Hydroboration of 1-alkynylboronate esters and in situ transmetalation furnishes 1-alkenyl-1,1-borozinc heterobimetallic intermediates. Reaction with aldehydes and in situ cyclopropanation generates B pin substituted cyclopropyl carbinols with excellent diastereoselectivities. Hussain, H. Li, N. Hussain, M. Xie, L. Zu, H.
Li, J. Wang, W. Wang, J. A modified O -TMS-diarylprolinol incorporating a hydrophobic alkyl side chain has been identified as a promising catalyst for this reaction. Uria, J. Vicario, D.
Carrillo, E. Reyes, A. Pesquera, Synthesis , , An efficient solvent-controlled oxidative cyclization of Michael adducts of malonates with chalcones with the combination of iodosobenzene and tetrabutylammonium iodide enables the divergent synthesis of highly functionalized oxetanes and cyclopropanes in good yields with high diastereoselectivity.